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The scope of these guidelines is to provide science-based guidance on processes and methodology for risk analysis and its application to foodborne AMR related to non-human use of antimicrobial agents. The guidelines aim to assess the risk to human health associated with the presence in food and animal feed, including aquaculture, and the transmission through food and animal feed, of AMR microorganisms and determinants, to provide advice on appropriate risk management activities to reduce such risk. The guidelines will further address the risk associated with different sectors of antimicrobial agent use such as veterinary applications, plant protection or food processing. 8. As there are existing Codex or internationally recognized guidelines, the following areas related to antimicrobial agents or AMR are outside the scope of this document: residues of antimicrobial agents in food; AMR marker genes in recombinant-DNA plants and recombinant DNA microorganisms 8 ; nongenetically modified microorganisms (for example, starter cultures) intentionally added to food with a technological purpose9; and certain food ingredients, which could potentially carry AMR genes, such as probiotics10